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Remdesivir, an injectable anti-viral drug repurposed for Covid-19 treatment, has been flying off the shelves of pharmacies over the last few weeks ever since India began reporting a steep rise in cases of the novel coronavirus. At least three states --  Gujarat and Maharashtra -- have reported shortages of the experimental therapy drug.

Why is this medication prescribed?

Remdesivir injection is used to treat coronavirus disease 2019 (COVID-19 infection) caused by the SARS-CoV-2 virus in hospitalized adults and children 12 years of age and older who weigh at least 88 pounds (40 kg). Remdesivir is in a class of medications called antivirals. It works by stopping the virus from spreading in the bodY

How should this medicine be used?

Remdesivir comes as a solution (liquid) and as a powder to be mixed with liquid and infused (injected slowly) into a vein over 30 to 120 minutes by a doctor or nurse in a hospital. It is usually given once daily for 5 to 10 days. The length of your treatment depends on how well your body responds to the medication.

Remdesivir injection may cause serious reactions during and after the infusion of the medication. A doctor or nurse will monitor you carefully while you are receiving the medication. Tell your doctor or nurse immediately if you experience any of the following symptoms during or after the infusion: chills or shivering; nausea; vomiting; sweating; dizziness upon standing up; rash; wheezing or shortness of breath; abnormally fast or slow heartbeat; or swelling of the face, throat, tongue, lips, or eyes. Your doctor may need to slow down your infusion or stop your treatment if you experience these side effects.

Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.

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What is remdesivir?

Remdesivir is used to treat people with coronavirus disease 2019 (COVID-19) who are in a hospital.

Remdesivir is for use in adults and children at least 12 years old and weighing at least 88 pounds (40 kilograms).

Remdesivir may also be used for purposes not listed in this medication guide.

How is remdesivir given?

Your doctor will perform blood tests to make sure you do not have conditions that would prevent you from safely using remdesivir.

Remdesivir is given as an infusion into a vein. A healthcare provider will give you this injection.

remdesivir must be given slowly, and the infusion can take 30 to 120 minutes to complete.

Remdesivir is usually given once per day for 5 to 10 days.

You will need frequent blood tests to check your liver function.

You must remain under the care of a doctor while you are being treated with remdesivir for COVID-19.

What other drugs will affect remdesivir?

Tell your doctor if you also take chloroquine or hydroxychloroquine. Either of these other medicines could make remdesivir less effective.

Other drugs may affect remdesivir, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.